Dr. Richard Horowitz joins me for a powerful conversation about Lyme disease, complex chronic illness, his new research exploring a connection between Lyme disease and Alzheimer’s disease, updates on his dapsone combination therapy, and his upcoming book, Ending Chronic Illness.
Drawing from more than four decades of clinical experience and research, Dr. Horowitz shares what he has learned about persistent forms of Borrelia, biofilms, inflammation, and why some people remain chronically ill despite years of treatment.
We dive into his fascinating newly published research exploring a possible connection between Lyme disease and Alzheimer’s disease, including phosphorylated tau and amyloid-beta, and what these findings could mean for understanding infections, inflammation, and chronic illness.
Dr. Horowitz also shares more about his new book, Ending Chronic Illness, available October 13, 2026. Bringing together over four decades of clinical experience and research, the book offers a comprehensive roadmap for understanding why people remain chronically ill, what factors may be driving their symptoms, and where to look next for answers.
Episode Resources:
New Book: Ending Chronic Illness - Available October 13, 2026
Lyme Disease & Alzheimer's Research: Journal of Alzheimer's Disease Reports https://journals.sagepub.com/doi/10.1177/25424823261445434
Dr. Horowitz's Breakdown of the Research: Medical Detective https://medicaldetective.substack.com/p/alzheimers-disease-and-lyme-disease-proving-for-the-first-time-ever-the-role-of-msids-factors-and-the-infection-amyloid-phosphorylated-tau-connection
Connect with Dr. Richard Horowitz: https://CanGetBetter.com
Facebook: Dr. Richard Horowitz
Instagram: @DrRichardHorowitz
Substack: Medical Detective: https://medicaldetective.substack.com
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